Blaze

The Blaze is the last mob encountered in the Nether area.

Strategy
The Blaze can run over plants, killing them instantly and they are also immune to fire. So kill them quickly with high power plants or non-fire instant kills. They will shoot every 3 seconds and will have a 7 second cool-down rate.

Trivia

 * The Blaze technically isn't a creature, but rather a robot.